Innovations Into Success Summer 2016 | Page 81

Laboratories : Case Study range includes highly validated neural stem cells , cortical neurons , dopaminergic neuron precursors and astrocytes from healthy and disease backgrounds including Alzheimer ' s and Huntington ' s diseases .
Axol ’ s cardiovascular range comprises of iPSC-derived cardiomyocytes from healthy donors , which beat spontaneously in culture and exhibit several cardiac-selective markers . The primary cell product range includes fibroblasts , haematopoietic , epithelial , mesenchymal and muscle cells . The most recent additions are the uncultured hepatocytes , assay-ready expanded ( ARE ) hepatocytes and liver sinusoidal epithelial cells .
Axol also offers a complete suite of custom services including custom donor cell sourcing , reprogramming and characterisation services . It specialises in directed differentiation of iPSCs to generate pure populations of functional cell types including cardiomyocytes , endothelial cells , and cerebral cortical , dopaminergic and sensory neural cells . Axol can also produce isogenic and reporter cell lines for disease modelling and drug discovery using CRISPR / Cas9 and iPSC technologies to edit the genome of disease-relevant cell types to create cellular models of genetic conditions .
In addition to expanding its range of product and service offerings , Axol has appointed a host of experts from academia and industry to ensure continued success . This includes Chief Scientific Officer , Xianmin Zeng , PhD , an Associate Professor at the Buck Institute for Research on Aging who is an expert in the development of stem cell disease models for neurodegenerative disorders and Chief Business Officer , Sanj Kumar who with more than 20 years ’ experience in leading
Axol Bioscience offices in the Science Village at Chesterford Research Park
biotechnology companies , is helping to create and execute the company ’ s commercial strategy .
Axol also announced several advisory board members earlier this year namely , Darrin Disley , PhD and Chris Torrance , PhD of Horizon Discovery ; Steve Rees , PhD of AstraZeneca ; Chas Bountra , PhD at the University of Oxford ; Paul Andrews , PhD from the National Phenotypic Screening Centre and Maria-

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