HeadWise Volume 4, Issue 3 | Page 16

C urrently, an estimated 12 million or more severe of the trigeminal nerve and resultant depletion of calcitonin as a nasal spray, Ausanil® specifically works locally in the lasted between 2 to 10 minutes. However, the majority headache and migraine patients are dissatisfied with gene-related peptides (CGRP), which have been identified nose, does not cause stomach or liver issues, and is safe to of patients noted that the sting would not dissuade them therapies available to them. They continuously search for as the “pain” neurotransmitters responsible for migraine use for patients with kidney or cardiovascular issues. from using the medication again for pain relief. additional treatment options that may provide fast relief pain. Reduction in the release of CGRP leads to a decrease of their pain without the limitations of adverse drug in the swelling and inflammation of blood vessels that The manufacturers of Ausanil® developed instructions for first time users: seems to give them relief or they’re limited on treatments interactions, systemic side effects, or for some individuals surround the brain, thus resulting in pain relief. due to drug-drug interactions or notable side effects, it “When you see a patient time and time again and nothing Specifically targeting the source of headache pain, the can be a very frustrating and heartbreaking process,” said For several decades, research has demonstrated that nasal spray is intended to provide rapid relief. According to a Maria Alexianu, MD, PhD of the Atlantic Neuroscience administration of extracts from the oleoresin capsicum real-world patient analysis presented at the 2014 American Institute at Overlook Medical Center in Summit, NJ. “It’s plant (chili pepper plant), such as capsaicin, have been Academy of Neurology (AAN) Annual Meeting, nearly 83 vital that we are able to offer new options like Ausanil® effective in treating migraine and cluster headaches. A percent of patients reported onset of relief within 1 to 3 to patients who are still searching for pain relief and are non-prescription, homeopathic nasal spray is now available minutes of use with the treatment. continuously incapacitated in their daily life.” – accessibility and affordability. • Only use Ausanil® in the nostril of the same side you are experiencing pain • Before using, prime the spray 1 to 2 times – away from your face • When using Ausanil®, aim the spray towards the outer part of your nasal cavity, not towards your nasal septum • DO NOT inhale Ausanil® upon use • After a minute of use, blow your nose Non-prescription Ausanil® is currently available for purchase online at Ausanil.com and at select pharmacies throughout the U.S. Each bottle retails for $34.95 per bottle and includes approximately 50 doses per bottle. HW which was specifically formulated using raw extract of the Although free of systemic side effects, when used chili pepper, capsicum annuum. It is observed to be a viable challenges headache sufferers confront, developers of the correctly, non-prescription Ausanil® will sting upon use. treatment option for many patients in search of rapid pain treatment, Ausanil®, worked to ensure that only small This stinging sensation is part of the mechanism of action relief from severe headaches, including migraine, cluster, quantities of the nasal spray are needed for rapid pain and is an indication that the treatment is working. Results and tension-type headaches. relief. This allows patients to use it in addition to other from the AAN patient analysis found that all patients Contributors: Reena Patel & Mary Franklin Acting locally in the nose, this non-prescription spray is medications, including triptans and over-the-counter pain experienced the local adverse event of the nasal sting, which Photo credit: Franz Eugen Köhler, Köhler’s Medizinal-Pflanzen thought to work by the calcium-mediated desensitization 16 Attempting to address one of the biggest common relievers, without adverse drug interactions. Additionally, HeadW ise ® | Volume 4, Issue 3 • 2015 www.headaches.org | National Headache Foundation 17