other treatment approaches. Most medications used for
refractory headaches are considered “off-label:” they were
initially developed for another purpose. How is a medication selected that is best suited for the individual? Comorbidities must be identified. These include the psychiatric
and medical conditions, other than headaches, that occur
in the individual. If someone has anxiety/depression, antidepressants may be prescribed. If weight gain is a major
issue, drugs associated with weight