Diagnostic Evidence Co-operatives (DECs)
Funded by the NIHR, the Diagnostic Evidence Co-operatives:
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Act as catalysts for the generation of high-quality evidence of clinical
validity, clinical utility, cost effectiveness and care pathway benefits of
commercially-supplied IVDs
Enable collaboration between the IVD industry, clinicians and other
healthcare professionals, patients, at least one accredited provider of
NHS pathology services, NHS commissioners, academic researchers
including health economists, and patient groups
Create new, world-class methodologies for IVD assessment.
Diagnostic Evidence Co-operatives Business Model
Each DEC provides a network of partners and collaborators who form a rich source
of expertise and resources for IVD evaluation. The DECs will draw upon the most
appropriate resources to match the needs of your project.
The DECs will work with you to put in place the legal and contractual documentation
that is appropriate for the specific study being undertaken. Depending on the individual
company needs, DECs can provide a variety of contracting options to clients, including
fee for contract services, collaborative project services or risk reward type arrangements.
Charging for services of the DEC is dependent upon the nature of the project and its
stage of development. The DECs will work with companies to determine the most suitable
charging option. DECs can also offer expert opinion and can assist companies to identify
and apply for relevant grant funding.
IVD Evaluation Methodology
NOCRI provides a single point of contact to each of the four NIHR DECs to
enable easy access to NHS expertise for the evaluation of in vitro
diagnostics.
Diagnostic Evidence Co-operatives: NHS organisations and clinical themes
NIHR Leeds Teaching
Hospitals NHS Trust
DEC
Generating high quality
evidence on protein and cellular
biomarker-based IVDs for the
clinical management of
musculoskeletal, urological, liver
and colorectal diseases and
oncology
www.leeds.dec.nihr.ac.uk
NIHR Newcastle upon
Tyne Hospitals NHS
Foundation Trust DEC
Generating high quality
evidence for new diagnostics tests
for cancer, cardiovascular, liver,
musculoskeletal and respiratory
diseases, stroke, genetics,
infections and transplantation
www.newcastle.dec.nihr.ac.uk
The DECs are playing a key role in researching and developing evaluation methodologies
for IVDs. This is predominantly in response to the needs of the NHS and the IVD industry,
and aims to generate robust evidence in a more timely and cost effective manner.
All four DECs are collaborating, via the DEC Methodology Group, to work on common
IVD evaluation methodologies, including study design, health economics and informatics.
Additionally, each DEC will draw on expertise in specific disease and technology areas to
make sure methodologies are developed for various different types of IVDs such as point
of care tests, primary care diagnostics and laboratory assays.
The DEC Methodology Group includes representation from the National Institute for
Health and Care Excellence (NICE) to help ensure that evidence generated through the
DEC process is relevant to the NICE Diagnostics Assessment Programme.
Further information about NIHR Diagnostic Evidence
Co-operatives
NIHR Oxford Health NHS
Foundation Trust DEC
Generating high quality
evidence for primary care IVDs
across a range of common
diseases and improving “bench
to bedside” processes to
implement IVDs into primary
care
www.oxford.dec.nihr.ac.uk
NIHR Imperial College
Healthcare NHS DEC
Generating high quality
evidence for point-of-care in vitro
diagnostic tests for gut health,
primary and general care,
respiratory disease, infectious
disease, metabolic medicine,
cardiovascular disease, cancer,
women’s health and paediatrics
www.london.dec.nihr.ac.uk
For more information about the DECs, or to understand how to work with the DECs,
contact NOCRI.
If you have any specific questions or would like to have an informal discusson with
NOCRI about the development of your technology, e-mail [email protected]
NIHR Office for Clinical Research Infrastructure (NOCRI)
146B, Skipton House, 80 London Road, London SE1 6LH
Web: www.nocri.nihr.ac.uk • E-Mail: [email protected] • Twitter: @NIHR_NOCRI
Diagnostic Evidence Co-operatives
generating the right evidence to help adoption of
commercial IVDs into the NHS