CardioSource WorldNews Interventions

CardioSource WorldNews vol 4, no 2 / MARCH/APRIL 2015 A publication of the American College of Cardiology INTERVENTIONS SUDDEN CARDIAC D E AT H post-PCI and post-MI 15 in post-PCI patients are at Ejection Fraction high risk of dying. (1) is the most powerful predictor of long-term mortality.(1) The majority of mortality in post-PCI patients with low EF occurs in the 2.5 2.0 3 first 2.5 2.0 1.5 months.(1) LVEF ≤ 30% (n=3852) LVEF 31-40% (n=4998) 1.0 Assess It. Discuss It. Prevent It. The risk of SCD post-MI is highest during the first 30 days. (2,3) 1.5 Rate of Sudden Death or Cardiac Arrest with Resuscitation (%/mo) 1.0 EF > 40% (n=2406) Post-MI patients with HF are at 4-6 times 0.5 0.5 greater risk of SCD in the first 30 days 1 2 3 4 5 6 12 24 36 48 after MI. (2,3) MI 85% HF+MI 3 month mortality BOTTOM LINE 1in10 high-risk post-PCI patients die, with about first 3 months post-PCI.(1) The CADILLAC Trial High-risk post-PCI patients experience significant mortality during recovery from revascularization. of 1 year mortality occurs in the 60% post-PCI (1) 11% Cleveland Clinic Registry 13% 12% EF ≤35% - post-PCI (4) Without STEMI 32% CATH PCI - NCDR Registry EF <30% post-PCI >65yo (5) With STEMI of this mortality due to SUDDEN CARDIAC DEATH. (1,6) SOURCES: 1. Halkin A et al. Prediction of Mortality After Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction: CADILLAC Risk Score. JACC 2005;45:1397–1405. 2. Adabag AS et al. Sudden Death After Myocardial Infarction. JAMA 2008;300:2022–2029. 3. Solomon SD et al. Sudden Death in Patients with Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both. NEJM 2005;352:2581–2588. 4. Zishiri ET et al. Early Risk of Mortality after Coronary Artery Revascularization in Patients with Left Ventricular Dysfunction and Potential Role of the Wearable Cardioverter Defibrillator. Circulation: Arrhythmia and Electrophysiology.2013;6:117–128. 5. Weintraub WS et al. Prediction of Long-Term Mortality After Percutaneous Coronary Intervention in Older Adults: Results From the National Cardiovascular Data Registry. Circulation: 2012;125:1501–1510. 6. Stone G et al. Prevention of Sudden Cardiac Arrest Post PTCA in High-Risk Patients. http://www.theheart.org/article/1202823.do (April 2011). ©2014 ZOLL Medical Corporation. All rights reserved. ZOLL and LifeVest are trademarks and/or registered trademarks of ZOLL Medical Corporation in the United States and/or other countries. 20C0312revA