CardioSource WorldNews Interventions
CardioSource
WorldNews
vol 4, no 2 / MARCH/APRIL 2015
A publication of the
American College
of Cardiology
INTERVENTIONS
SUDDEN
CARDIAC
D E AT H
post-PCI and post-MI
15
in
post-PCI
patients are at
Ejection Fraction
high risk of dying.
(1)
is the most powerful predictor
of long-term mortality.(1)
The majority of mortality
in post-PCI patients
with low EF occurs in the
2.5
2.0
3
first
2.5
2.0
1.5
months.(1)
LVEF ≤ 30% (n=3852)
LVEF 31-40% (n=4998)
1.0
Assess It.
Discuss It.
Prevent It.
The risk of SCD post-MI
is highest during the
first 30 days. (2,3)
1.5
Rate of Sudden Death or
Cardiac Arrest with Resuscitation
(%/mo)
1.0
EF > 40% (n=2406)
Post-MI patients with HF are at
4-6 times
0.5
0.5
greater risk of SCD in the
first 30 days
1 2 3 4 5 6
12
24
36
48
after MI. (2,3)
MI
85%
HF+MI
3
month
mortality
BOTTOM LINE
1in10
high-risk post-PCI patients die,
with about
first 3 months
post-PCI.(1)
The CADILLAC Trial
High-risk post-PCI patients
experience significant
mortality during recovery
from revascularization.
of 1 year mortality
occurs in the
60%
post-PCI (1)
11%
Cleveland Clinic Registry
13%
12%
EF ≤35% - post-PCI (4)
Without
STEMI
32%
CATH PCI - NCDR Registry
EF <30%
post-PCI >65yo (5)
With
STEMI
of this mortality
due to
SUDDEN CARDIAC DEATH.
(1,6)
SOURCES: 1. Halkin A et al. Prediction of Mortality After Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction: CADILLAC Risk Score. JACC 2005;45:1397–1405. 2. Adabag AS
et al. Sudden Death After Myocardial Infarction. JAMA 2008;300:2022–2029. 3. Solomon SD et al. Sudden Death in Patients with Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure,
or Both. NEJM 2005;352:2581–2588. 4. Zishiri ET et al. Early Risk of Mortality after Coronary Artery Revascularization in Patients with Left Ventricular Dysfunction and Potential Role of the Wearable
Cardioverter Defibrillator. Circulation: Arrhythmia and Electrophysiology.2013;6:117–128. 5. Weintraub WS et al. Prediction of Long-Term Mortality After Percutaneous Coronary Intervention in
Older Adults: Results From the National Cardiovascular Data Registry. Circulation: 2012;125:1501–1510. 6. Stone G et al. Prevention of Sudden Cardiac Arrest Post PTCA in High-Risk Patients.
http://www.theheart.org/article/1202823.do (April 2011).
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